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Cerner Corp lasix 100mg price generic lasix prices. Is expanding its healthcare data and technology business with plans to acquire consultancy Kantar Health for $375 million, the companies said Wednesday.Kantar Health, a division of Kantar Group, focuses primarily on data, analytics and research in the life science industry, but Cerner hopes to use their data more broadly to improve safety and efficacy, according to the companies' announcement. It will look to foster collaboration between providers and drugmakers on clinical research.Cerner this month lasix 100mg price also partnered with Elligo to expand clinical trial resources for rural and community health providers. The company hopes the data and arrangements will help their clients innovate in clinical research and find more effective treatments."Kantar Health has incredible health economics and medical affairs expertise, differentiated real-world data assets and strong relationships with the world's leading life science companies," Cerner's President Donald Trigg said in a statement.

"It offers us an amazing opportunity to drive cross-industry collaboration that can change health outcomes around the world." The acquisition is lasix 100mg price expected to close in the first half of 2021, subject to regulatory approval. Cerner said it will not have a material impact on its earnings, and it is paying cash for Kantar Health..

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NSW Health has revised the hypertension medications re period from 12 weeks down to four weeks effective from today.People who have previously had lasix 100mg price hypertension medications should test for hypertension medications after 28 days since their isolation ended if experiencing symptoms and follow the relevant health advice if they test positive. People who lasix 100mg price test positive again will be reported and managed as new cases. NSW Chief Health Officer Dr Kerry Chant said the reduced re period, which follows the advice from the Australian Health Protection Principal Committee, is due to the latest subvariants of Omicron circulating lasix 100mg price in the community.“The Omicron BA.4 and BA.5 subvariants are circulating widely in NSW. They are more able to evade immunity gained from previous and vaccination re is more likely and possible just weeks lasix 100mg price after a prior ,” Dr Chant said.“We’re urging people who have recently had hypertension medications, even if they left isolation in the past four weeks, not to be complacent.

If you lasix 100mg price develop symptoms again, make sure to test and isolate.”Dr Chant is also urging members of the community who are now eligible for a hypertension medications booster dose to access it as soon as possible ahead of an expected peak in cases in the coming weeks. The expansion of the winter booster program means those aged 50 to 64 years are now recommended lasix 100mg price to receive a second or winter booster dose, which is available to all those aged 30 and over.“With the rising number of hypertension medications cases in the community driven by a wave of wave of BA.4 and BA.5 s, it is vital people are up to date with their hypertension medications vaccinations, as this will provide the best protection against severe illness from hypertension medications,” Dr Chant said. Dr Chant said while most cases of hypertension medications are mild, some members of the community are at a risk of severe and may be able to access antiviral medications to treat their .“Antivirals work best when taken at the beginning of a hypertension medications , so it is really important that if you are at high risk, you plan ahead, speak with a doctor so you understand the treatment options which are available to you if you test positive for hypertension medications,” Dr Chant said.All members of the community are being asked to do little things that reduce the risk for more vulnerable members of the community and make a big difference, including by:staying up to date with our vaccinations – for both flu and hypertension medicationsstaying home if unwell, taking a hypertension medications test and self-isolating wearing a mask in public indoor spacesgetting together outdoors or in large, well-ventilated spaces with open doors and windowspractising good hygiene by washing or sanitising our hands taking a rapid antigen test for hypertension medications before visiting vulnerable loved ones or going to large gatherings and events..

NSW Health has revised the hypertension medications re period lasix 100mg price from 12 weeks down to four weeks effective from today.People who have previously learn this here now had hypertension medications should test for hypertension medications after 28 days since their isolation ended if experiencing symptoms and follow the relevant health advice if they test positive. People who test positive again will be reported and lasix 100mg price managed as new cases. NSW Chief Health Officer Dr Kerry Chant said the reduced re period, which follows the advice lasix 100mg price from the Australian Health Protection Principal Committee, is due to the latest subvariants of Omicron circulating in the community.“The Omicron BA.4 and BA.5 subvariants are circulating widely in NSW. They are more able to evade immunity gained from previous and vaccination re is more likely and possible just weeks after a prior ,” Dr Chant said.“We’re urging lasix 100mg price people who have recently had hypertension medications, even if they left isolation in the past four weeks, not to be complacent. If you develop symptoms again, make sure to test and isolate.”Dr Chant is also urging members of the community lasix 100mg price who are now eligible for a hypertension medications booster dose to access it as soon as possible ahead of an expected peak in cases in the coming weeks.

The expansion of the winter booster program means those aged 50 to 64 years are now recommended to receive a second or winter booster dose, which is available to all those aged 30 lasix 100mg price and over.“With the rising number of hypertension medications cases in the community driven by a wave of wave of BA.4 and BA.5 s, it is vital people are up to date with their hypertension medications vaccinations, as this will provide the best protection against severe illness from hypertension medications,” Dr Chant said. Dr Chant said while most cases of hypertension medications are mild, some members of the community are at a risk of severe and may be able to access antiviral medications to treat their .“Antivirals work best when taken at the beginning of a hypertension medications , so it is really important that if you are at high risk, you plan ahead, speak with a doctor so you understand the treatment options which are available to you if you test positive for hypertension medications,” Dr Chant said.All members of the community are being asked to do little things that reduce the risk for more vulnerable members of the community and make a big difference, including by:staying up to date with our vaccinations – for both flu and hypertension medicationsstaying home if unwell, taking a hypertension medications test and self-isolating wearing a mask in public indoor spacesgetting together outdoors or in large, well-ventilated spaces with open doors and windowspractising good hygiene by washing or sanitising our hands taking a rapid antigen test for hypertension medications before visiting vulnerable loved ones or going to large gatherings and events..

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FORT MYERS, FL – An investigation by the U.S lasix side effects on kidneys. Department of Labor’s Wage and Hour Division has recovered more than $36,000 in back wages for workers at a grocery store that denied them overtime pay required by the Fair Labor Standards Act. At Pica lasix side effects on kidneys Italian Deli Inc. €“ operating as Mario’s Italian Meat Market – investigators found the employer paid two deli clerks, one cook and one stocker, flat salaries regardless of the number of hours they worked each workweek.

By doing lasix side effects on kidneys so, the employer violated FLSA overtime requirements when these employees worked more than 40 hours in a workweek, yet they failed to pay them overtime. As a result, the division recovered $36,279 in overtime back wages for the four workers. The employer also violated lasix side effects on kidneys FLSA recordkeeping requirements by failing to track the number of hours these employees worked each workweek. €œSome employers believe incorrectly that simply paying an employee a flat salary automatically means they don’t have to pay those workers overtime.

That is lasix side effects on kidneys not true,” said Wage and Hour Division District Director Nicolas Ratmiroff in Tampa, Florida. €œAny exemptions from the law’s overtime provisions require that very specific criteria be met. We hope this investigation’s outcome encourages other employers to review their own pay lasix side effects on kidneys practices to ensure they avoid similar violations and comply with the law.” For more information about the FLSA and other laws enforced by the division, contact the agency’s toll-free helpline at 866-4US-WAGE (487-9243). Learn more about the Wage and Hour Division, including a search tool to use if you think you may be owed back wages collected by the division.WASHINGTON, DC – U.S.

Secretary of Labor Marty Walsh issued the following statement on the lasix side effects on kidneys April 2021 Employment Situation Report:“Today, the Bureau of Labor Statistics reported that the American economy added 266,000 jobs in the month of April, and the unemployment rate was 6.1 percent, up marginally from 6.0 percent in March. Labor force participation is at its highest point since last August and the number of people expressing hesitancy about returning to work due to the hypertension is at its lowest point in the lasix. “However, the numbers also show lasix side effects on kidneys we have a steep climb ahead of us. We have yet to recover roughly eight million jobs that existed prior to the lasix.

Racial inequities in the unemployment picture persist, as the Black unemployment rate increased lasix side effects on kidneys slightly to 9.7 percent, the Hispanic rate held level at 7.9 percent, the Asian rate dropped to 5.7 percent and the white rate fell to 5.3 percent. “These figures underscore how the American Rescue Plan puts us on the path to recovery. It’s increased the speed and access of vaccinations, it’s bringing needed relief to families, it’s enabling daycare centers and schools to reopen, and it’s supporting lasix side effects on kidneys small businesses. It’s going to take time and effort to heal this economy.”.

FORT MYERS, click FL – An investigation by the lasix 100mg price U.S. Department of Labor’s Wage and Hour Division has recovered more than $36,000 in back wages for workers at a grocery store that denied them overtime pay required by the Fair Labor Standards Act. At Pica Italian lasix 100mg price Deli Inc. €“ operating as Mario’s Italian Meat Market – investigators found the employer paid two deli clerks, one cook and one stocker, flat salaries regardless of the number of hours they worked each workweek. By doing so, the employer violated FLSA overtime requirements when these employees worked more than 40 hours in a workweek, yet they failed to pay them overtime lasix 100mg price.

As a result, the division recovered $36,279 in overtime back wages for the four workers. The employer also violated FLSA recordkeeping requirements by failing to track the lasix 100mg price number of hours these employees worked each workweek. €œSome employers believe incorrectly that simply paying an employee a flat salary automatically means they don’t have to pay those workers overtime. That is not true,” said Wage and lasix 100mg price Hour Division District Director Nicolas Ratmiroff in Tampa, Florida. €œAny exemptions from the law’s overtime provisions require that very specific criteria be met.

We hope this investigation’s outcome encourages other employers to review their own pay practices to lasix 100mg price ensure helpful site they avoid similar violations and comply with the law.” For more information about the FLSA and other laws enforced by the division, contact the agency’s toll-free helpline at 866-4US-WAGE (487-9243). Learn more about the Wage and Hour Division, including a search tool to use if you think you may be owed back wages collected by the division.WASHINGTON, DC – U.S. Secretary of Labor Marty Walsh issued the following statement on the April 2021 Employment Situation lasix 100mg price Report:“Today, the Bureau of Labor Statistics reported that the American economy added 266,000 jobs in the month of April, and the unemployment rate was 6.1 percent, up marginally from 6.0 percent in March. Labor force participation is at its highest point since last August and the number of people expressing hesitancy about returning to work due to the hypertension is at its lowest point in the lasix. “However, the numbers also show we have a steep climb lasix 100mg price ahead of us.

We have yet to recover roughly eight million jobs that existed prior to the lasix. Racial inequities in the unemployment picture persist, as the Black unemployment rate increased slightly to 9.7 percent, the Hispanic rate held lasix 100mg price level at 7.9 percent, the Asian rate dropped to 5.7 percent and the white rate fell to 5.3 percent. “These figures underscore how the American Rescue Plan puts us on the path to recovery. It’s increased the speed and access of vaccinations, it’s bringing needed relief to families, it’s enabling daycare centers and schools to reopen, and it’s supporting small businesses. It’s going to take time and effort to heal this economy.”.

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With partner organisation the Guttmacher Institute, the WHO said that the results would allow health authorities to better understand family planning needs in their countries, including contraception and abortion care.According to the data – which represent the first such exercise at a country level - unintended pregnancy and abortion rates vary widely, even within the same region.Significant variationsThe greatest variations are in Latin America, where unintended pregnancy rates ranged from 41 to 107 per 1,000 women, and in sub-Saharan Africa, where the range was 49 to 145 women per 1,000.Even in regions with low unintended pregnancy rates, it is still hugely important to invest in giving women and girls the information they need to choose whether they want to have children, said the Guttmacher Institute’s Jonathan Bearak, whose study appears in the journal, BMJ Global Health.Essential health coverage“Sexual and reproductive health and rights are an essential part of universal health coverage and are required to end discrimination against women and girls,” the WHO lasix 12.5 said.These disparities are not shaped purely by income-level. In Europe, for example, most countries with higher unintended pregnancy rates than the regional average, are classified as high-income, while the two countries with the lowest estimates are in the middle-income category.This finding reflects how barriers to accessing and using effective sexual and reproductive healthcare, exist in all settings, not just those where resources are scarce.Abortion bans, ineffective “The proportion of unintended pregnancies ending in lasix 12.5 abortion - as great as 68%, even among countries that completely prohibited abortion - illustrates the strength of the desire of millions of women and adolescents to avoid unplanned childbearing”, said Mr. Bearak.While the estimates go a long way in increasing the quality of evidence available, there remains a pressing need for more and better data lasix 12.5. © PAHO/Fredy GomezWomen in La Paz, Bolivia, receive information on modern contraceptive methods.Fair investmentThese country-level estimates highlight the importance of equitable investment in comprehensive sexual and reproductive healthcare, and will further inform countries working to implement WHO’s new guidelines for quality abortion services.“For good health, people in countries around the world need access lasix 12.5 to a comprehensive package of sexuality education, accurate family planning information and services, as well as quality abortion care,” said Dr Bela Ganatra, who leads WHO’s Prevention of Unsafe Abortion unit.“This research aims to support countries as they work to strengthen the lifesaving services they provide for sexual and reproductive health and improve health outcomes - especially for women and girls.”Secretary-General António Guterres said that first and foremost, Ukraine needed support, towards ending the war, and to help the millions who have fled, return home.“Many developing countries were already struggling to recover from the economic impact of the hypertension medications lasix.

Record inflation lasix 12.5. Rising interest rates lasix 12.5. Unmanageable debt burdens”, he said, lasix 12.5 adding that now, “they face skyrocketing food, energy and fertilizer bills.”With donor fatigue setting in across the developed world, countries must come together, rich and poor, to find global solutions, “because this is a global crisis. “No country lasix 12.5 will be able to insulate itself from a meltdown of the global economic system.

From the domino effect of lasix 12.5 hoarding food or fuel. Or from the long-term impact of increased poverty and hunger”, he said.Resources are plentiful, but deep inequalities, distribution lasix 12.5 and logistics logjams, mean supply chains have been disrupted, and better coordinated action, is essential, Mr. Guterres added.Access for all“We need to get rid lasix 12.5 of bottlenecks, prevent hoarding and speculation, reform finance frameworks, to allow those that need money to buy things that are essential for their countries to have access to those funds - revisiting rules and eligibility criteria whenever necessary. Every country that needs support must be able to access it.”This, he said, was the remit of the Global Crisis Response Group, to include heads of State and government leaders, who have already volunteered support.“I have every confidence that this Steering Committee will provide the direction and focus needed for our decisions…From vulnerability indices to support strategies, we already have lasix 12.5 many of the pieces in place.

We need to repurpose, expand and build on them to create an effective, coordinated, system-wide response.” Tackling the global impact of the war, said the UN chief, will require the same unity and solidarity we have seen in the support given to Ukrainian refugees.“We must seize this moment and move forward together.” © WHO/Anastasia VlasovaA surgeon bandages an injured patient at Kyiv's Hospital, Ukraine.Tedros urges Russia to stop the warEarlier in the day, briefing journalists in Geneva, UN health agency chief Tedros Adhanom Ghebreyesus, said that a month since Russia’s invasion of Ukraine, people’s health needs there were dire, and only getting worse.The situation is particularly critical in the coastal city of Mariupol and elsewhere, Tedros said, where the World Health Organization (WHO) has not been able to dispatch a humanitarian convoy because of the ongoing violence.Other Ukrainian cities have received 150 tonnes of medical supplies from the WHO hub in Lviv in western Ukraine, but access to lasix 12.5 many locations “remains blocked”.Tedros issued an appeal to Russia “to stop the war”, before condemning ongoing attacks on hospitals, patients and medical staff:“WHO has now verified 64 attacks on health care since the start of the war and we are in the process of verifying further attacks. Attacks on health must lasix 12.5 stop. Health systems, facilities and workers are not and should never be a target.”He said that WHO also had concerns around the “integrity and safe operation of nuclear and chemical facilities.“WHO is working with the International Atomic Energy Agency (IAEA), and we continue to call on all sides to minimise the risk of a nuclear or chemical accident, which could have catastrophic consequences for human health.” IMF Photo/Joaquin SarmientoPeople wear face masks during the hypertension medications lasix in Medellín, Colombia.hypertension medications updateSumming up the latest global situation regarding the spread of hypertension medications, he said the increase in hypertension medications cases continues, “driven by large outbreaks in Asia and a fresh wave in Europe.”Several countries are now seeing their highest death rates since the beginning of the lasix, lasix 12.5 he remarked.This reflects the sheer speed of the Omicron variant, and the heightened risk of death for the unvaccinated.“We all want to move on from the lasix. But no matter how much we wish it away, this lasix is not over.

Until we reach high vaccination coverage in all countries, we will continue to face the risk of s surging, and new variants emerging that evade treatments.Even as some high-income countries propose a second booster dose, one third of the world’s population remains unvaccinated.But he said there were some “promising signs” of progress.In Nigeria, treatment uptake was dramatically increased when supply stabilized, and planning was done on how to effectively distribute treatments, the WHO chief noted.WHO will continue pushing for a 70% vaccination target for every country, by the middle of this year, with priority given to health workers, older people and other at-risk groups..

With partner organisation the Guttmacher Institute, the WHO said that the results would allow health authorities to better understand family planning needs in their countries, including contraception and abortion care.According to the data – which represent the first such exercise at a country level - unintended pregnancy and abortion rates vary widely, even within the same region.Significant variationsThe greatest variations are in Latin America, where unintended pregnancy rates ranged from 41 to 107 per 1,000 women, and in sub-Saharan Africa, lasix 100mg price where the range was 49 to 145 women per 1,000.Even in regions with low unintended pregnancy rates, it is still hugely important to invest in giving women and girls the information they need to choose whether they want to have children, said the Guttmacher Institute’s Jonathan Bearak, whose study appears in the journal, BMJ Global Health.Essential health coverage“Sexual and reproductive health and rights are an essential part of universal health coverage and are required to end discrimination against Buy cialis online safely women and girls,” the WHO said.These disparities are not shaped purely by income-level. In Europe, for example, most countries with higher unintended pregnancy rates than the regional average, are classified as high-income, while the lasix 100mg price two countries with the lowest estimates are in the middle-income category.This finding reflects how barriers to accessing and using effective sexual and reproductive healthcare, exist in all settings, not just those where resources are scarce.Abortion bans, ineffective “The proportion of unintended pregnancies ending in abortion - as great as 68%, even among countries that completely prohibited abortion - illustrates the strength of the desire of millions of women and adolescents to avoid unplanned childbearing”, said Mr. Bearak.While the estimates go a long way in increasing the quality of lasix 100mg price evidence available, there remains a pressing need for more and better data. © PAHO/Fredy GomezWomen in La Paz, Bolivia, receive information on modern contraceptive methods.Fair investmentThese country-level estimates highlight the importance of equitable investment in comprehensive sexual and reproductive healthcare, and will further inform countries working to implement WHO’s new guidelines for quality abortion services.“For good health, people in countries around the world need access to a comprehensive package of sexuality education, accurate family planning information and services, as well as quality abortion care,” said Dr Bela Ganatra, who leads WHO’s Prevention of Unsafe Abortion unit.“This research aims to support countries as they work to strengthen the lifesaving services they provide for sexual and reproductive health and improve health outcomes - especially for women and girls.”Secretary-General António Guterres said that first and foremost, lasix 100mg price Ukraine needed support, towards ending the war, and to help the millions who have fled, return home.“Many developing countries were already struggling to recover from the economic impact of the hypertension medications lasix.

Record inflation lasix 100mg price. Rising interest rates lasix 100mg price. Unmanageable debt burdens”, he said, adding that now, “they face skyrocketing food, lasix 100mg price energy and fertilizer bills.”With donor fatigue setting in across the developed world, countries must come together, rich and poor, to find global solutions, “because this is a global crisis. “No country will be able to insulate itself lasix 100mg price from a meltdown of the global economic system.

From the domino effect of hoarding food or fuel lasix 100mg price. Or from the long-term impact of increased poverty and hunger”, he said.Resources are plentiful, but deep inequalities, distribution and logistics logjams, mean supply chains have been disrupted, and better coordinated action, is essential, Mr lasix 100mg price. Guterres added.Access for all“We need to get rid of bottlenecks, prevent hoarding and speculation, reform finance frameworks, to allow those that need money to buy things that are essential for their countries to have access to those funds - revisiting lasix 100mg price rules and eligibility criteria whenever necessary. Every country that needs support must be able to access it.”This, he said, was the remit of the Global Crisis Response Group, to include heads of State and government lasix 100mg price leaders, who have already volunteered support.“I have every confidence that this Steering Committee will provide the direction and focus needed for our decisions…From vulnerability indices to support strategies, we already have many of the pieces in place.

We need to repurpose, expand and build on them to create an effective, coordinated, system-wide response.” Tackling the global impact of the war, said the UN chief, will require the same unity and solidarity we have seen in the support given to Ukrainian refugees.“We must seize this moment and move forward together.” © WHO/Anastasia VlasovaA surgeon bandages an injured patient at Kyiv's Hospital, Ukraine.Tedros urges Russia to stop the warEarlier in the day, briefing journalists in Geneva, UN health agency chief Tedros Adhanom Ghebreyesus, said that a month since Russia’s invasion of Ukraine, people’s health needs there were dire, and only getting worse.The situation is particularly critical in the coastal city of Mariupol and elsewhere, Tedros said, where the World Health Organization (WHO) has not been able to dispatch a humanitarian convoy because of the ongoing violence.Other Ukrainian cities have received 150 tonnes of medical supplies from the WHO hub in Lviv in western Ukraine, but access to many lasix 100mg price locations “remains blocked”.Tedros issued an appeal to Russia “to stop the war”, before condemning ongoing attacks on hospitals, patients and medical staff:“WHO has now verified 64 attacks on health care since the start of the war and we are in the process of verifying further attacks. Attacks on health lasix 100mg price must stop. Health systems, facilities and workers are not and should never be a target.”He said that WHO also had concerns around the “integrity and safe operation of nuclear and chemical facilities.“WHO is working with the International Atomic Energy Agency (IAEA), and we continue to call on all sides to minimise the risk of a nuclear or chemical accident, which could have catastrophic consequences for human health.” IMF Photo/Joaquin SarmientoPeople wear face masks during the hypertension medications lasix in Medellín, Colombia.hypertension medications updateSumming up the latest global situation regarding the spread of hypertension medications, he said the increase in hypertension medications cases continues, “driven by large outbreaks in Asia and a fresh wave in Europe.”Several countries lasix 100mg price are now seeing their highest death rates since the beginning of the lasix, he remarked.This reflects the sheer speed of the Omicron variant, and the heightened risk of death for the unvaccinated.“We all want to move on from the lasix. But no matter how lasix 100mg price much we wish it away, this lasix is not over.

Until we reach high vaccination coverage in all countries, we will continue to face the risk of s surging, and new variants emerging that evade treatments.Even as some high-income countries propose a second booster dose, one third of the world’s population remains unvaccinated.But he said there were some “promising signs” of progress.In Nigeria, treatment uptake was dramatically increased when supply stabilized, and planning was done on how to effectively distribute treatments, the WHO chief noted.WHO will continue pushing for a 70% vaccination target for every country, by the middle of this year, with priority given to health workers, older people and other at-risk groups..

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Literally literacyThough this issue won’t appear for another 3-4 weeks, given the painful events unravelling in Afghanistan, it would feel banal to the point of negligence to fail to ask ‘where http://www.securityresources.com/ventolin-price-cvs/ are we going’ in terms of global human rights.Many years ago, I took a short course on ‘primary health care in low and middle how to take lasix 40mg countries’ to equip myself with some knowledge of the public health issues I was likely to encounter first in Sudan and later Afghanistan. Though the teaching was a little too ‘touchy feely’ for my taste, it left an impression based on one talk and one message. Female literacy how to take lasix 40mg.

Once assimilated, I realised that this was central to everythingI was based close to Kabul, during the immediate, relatively upbeat (if not as openly urbane as the 1970s) post-Soviet withdrawal era and have maintained some contact in the form of research collaborations with colleagues in the Afghan Ministry of Health. In parallel, we have seen the tantalising promise of a future of freedom and children’s futures and women’s rights snatched away so abruptly, the purple period from 2001 to 2021 already feeling illusorySo, when the headlines change as they inevitably will (tabloid attention no doubt turning to the off-duty improprieties of a footballer or mid-ranking cabinet member) don’t forget that if classrooms can be kept open, then there is still hope.Global child health. Maternal and perinatal outcomeContinuing the neonatal how to take lasix 40mg sepsis theme discussed by Carolin Fleischmann and colleagues in the August issue (https://adc.bmj.com/content/106/8/745) Adama Baguiya’s WHO maternal sepsis (GLOSS) group takes another angle, the identification of high risk babies by the mothers’ peripartum condition.

Using data from 43 LMICs, neonatal outcomes of mothers with suspected or proven sepsis were compared with those in whom there were no concerns. The direction of effect (predictive) was perhaps not surprising, though the magnitude was. A third of the babies of how to take lasix 40mg these women had adverse outcomes.

25% near miss events (outcomes requiring intervention or resuscitation of some sort) and a 10% mortality with an OR of 3.8 (95% CI 2.0 to 7.1) for the most severely unwell mothers. How then can these women be identified earlier how to take lasix 40mg before both they and the fetus starts to decompensate?. See page 946Opiates in analgesiaWe all have a preferred opiate for analgesia resistant to first and second line alternatives and this particular choice has been, for as long as I can remember, if not divisive then factionalising.From buprenorphine patches to intranasal fentanyl to oral dextromoramide (the latter admittedly now largely a museum piece) to codeine, each has its (often vocal) proponents, the volume of their arguments not necessarily a correlate of analgesic effect.In the Drugs and Therapeutics section, Sarah Spenard and colleagues address this chestnut in their systematic review of the literature comparing morphine and hydromorphone, the turn to opioid in the face of the nausea and (histamine agonism-related) pruritus for which morphine itself is renowned.

They found high quality evidence from 4 RCTs concluding there was nothing to choose between them in terms of therapeutic or side effects. So, rather than weighing up which opiate, the only question worth asking is ‘is there a reason not to how to take lasix 40mg start one now?. €™ in the face of a child struggling on high dose NSAID treatment.

See page 1002Safety reportingWe are the proud discovers of a new antimicrobial drug, let’s call it ‘viroblast 21’, the performance of which in phase two trials has been (our brochures proclaim) ‘breathtaking’. Agog with how to take lasix 40mg excitement, we proceed to the ‘definitive’ randomised controlled trial in children admitted to PICU for respiratory support. The ‘fully adjusted analyses’ (inverted commas, of course intentional) repay the faith we had in the drug, a ‘jaw dropping’ protective HR in time to recovery of 0.2 (95% CI 0.1 to 0.35).

The tension is released and celebrations can begin… or can how to take lasix 40mg they?. The message in Taco Jan Pils’ and colleagues’ systematic review of trials reporting is that, even now, in the era of EQUATOR, CONSORT, siblings and half siblings safety data is often overlooked. Though reporting has improved over the decade since their previous review, it’s baffling that it isn’t 100%.

Part of the story is missing how to take lasix 40mg. Taking a tangential trajectory, it would be reasonable to argue that the sort of safety reporting leaves a few more loopholes. I want to know whether children can swallow the preparation.

Whether it tastes how to take lasix 40mg good (or at least isn’t emetogenic). And that the cost is not crippling for the health service or patients and parents by which it will ultimately be financed. This too (the economic burden) how to take lasix 40mg is also to my mind a side effect.

Where resources are finite, something else will have to give. Maybe that mouthwatering ‘effect size’ didn’t tell us everything we need to know. See page 1010Fixing a hole where the rain gets inThe reality is that much of what we do, despite the best public health preventative how to take lasix 40mg measures is reactive.

The asthmatic child’s parents of ‘who only ever smoke outside’ are advised to stop or get help/gum/patches.I’m digressing but only slightly as, what I’m getting at are the upstream (preventative) vs downstream (symptomatic) approaches. Until recently, all treatment in cystic fibrosis was, by necessity, reactive/downstream. The advent of the CF transmembrane modulator family, how to take lasix 40mg correctors and potentiators has changed all this.

Iolo Doull’s compelling review from the discovery of the molecule to the consistent improvements in all objective measures of lung and overall health by its augmentation testifies to this. This is how to take lasix 40mg exciting for other reasons too. In the same way that anti-retroviral treatment in HIV became bolder and gathered pace, there is impetus for novel orphan drug development with implications beyond CF alone.

See page 941(Pierre-)Robin sequence (RS) is characterised by mandibular retrognathia, glossoptosis and upper airway obstruction (UAO). To alleviate the latter, placing such infants prone was already suggested how to take lasix 40mg as a first-line treatment by Robin himself, the eponym of this condition. Indeed, it appears intuitively plausible that gravity will help shifting the mandible forward during sleep.

Against this background, it was not surprising that the prone position was implemented by about two-thirds of respondents to a recent survey focusing on interventions used in infants with RS.1In neonatology, however, we have learnt the hard way that what seems plausible is not always effective and, particularly, safe. Thus, we need to scrutinise the evidence for how to take lasix 40mg recommending prone positioning to resolve UAO in infants with RS. Objective data on the effectiveness of this intervention, however, are sparse.

A retrospective analysis of sleep study data in 18 infants with RS (mean age, 1.5 months) found a higher sleep efficiency in the prone position, but no significant reduction in the severity of obstructive sleep apnoea (OSA).2 A longitudinal prospective study in 14 infants with RS (mean age, 1.8 months) reported a median Obstructive Apnoea–Hypopnoea ….

Literally literacyThough Ventolin price cvs this issue won’t appear for another 3-4 weeks, given the painful events unravelling in Afghanistan, it would feel banal to the point of negligence to fail to ask ‘where are we going’ in terms of global human rights.Many years ago, I took a short course on ‘primary health care in low and middle countries’ to equip myself with some knowledge of the public health issues I was likely to encounter first lasix 100mg price in Sudan and later Afghanistan. Though the teaching was a little too ‘touchy feely’ for my taste, it left an impression based on one talk and one message. Female literacy lasix 100mg price.

Once assimilated, I realised that this was central to everythingI was based close to Kabul, during the immediate, relatively upbeat (if not as openly urbane as the 1970s) post-Soviet withdrawal era and have maintained some contact in the form of research collaborations with colleagues in the Afghan Ministry of Health. In parallel, we have seen the tantalising promise of a future of freedom and children’s futures and women’s rights snatched away so abruptly, the purple period from 2001 to 2021 already feeling illusorySo, when the headlines change as they inevitably will (tabloid attention no doubt turning to the off-duty improprieties of a footballer or mid-ranking cabinet member) don’t forget that if classrooms can be kept open, then there is still hope.Global child health. Maternal and perinatal outcomeContinuing the neonatal sepsis theme discussed by Carolin Fleischmann and colleagues in the August issue (https://adc.bmj.com/content/106/8/745) Adama Baguiya’s WHO maternal sepsis (GLOSS) group lasix 100mg price takes another angle, the identification of high risk babies by the mothers’ peripartum condition.

Using data from 43 LMICs, neonatal outcomes of mothers with suspected or proven sepsis were compared with those in whom there were no concerns. The direction of effect (predictive) was perhaps not surprising, though the magnitude was. A third lasix 100mg price of the babies of these women had adverse outcomes.

25% near miss events (outcomes requiring intervention or resuscitation of some sort) and a 10% mortality with an OR of 3.8 (95% CI 2.0 to 7.1) for the most severely unwell mothers. How then can these women be identified lasix 100mg price earlier before both they and the fetus starts to decompensate?. See page 946Opiates in analgesiaWe all have a preferred opiate for analgesia resistant to first and second line alternatives and this particular choice has been, for as long as I can remember, if not divisive then factionalising.From buprenorphine patches to intranasal fentanyl to oral dextromoramide (the latter admittedly now largely a museum piece) to codeine, each has its (often vocal) proponents, the volume of their arguments not necessarily a correlate of analgesic effect.In the Drugs and Therapeutics section, Sarah Spenard and colleagues address this chestnut in their systematic review of the literature comparing morphine and hydromorphone, the turn to opioid in the face of the nausea and (histamine agonism-related) pruritus for which morphine itself is renowned.

They found high quality evidence from 4 RCTs concluding there was nothing to choose between them in terms of therapeutic or side effects. So, rather than weighing up which opiate, the only question worth asking is ‘is there a reason not to start one lasix 100mg price now?. €™ in the face of a child struggling on high dose NSAID treatment.

See page 1002Safety reportingWe are the proud discovers of a new antimicrobial drug, let’s call it ‘viroblast 21’, the performance of which in phase two trials has been (our brochures proclaim) ‘breathtaking’. Agog with excitement, we proceed to the ‘definitive’ randomised lasix 100mg price controlled trial in children admitted to PICU for respiratory support. The ‘fully adjusted analyses’ (inverted commas, of course intentional) repay the faith we had in the drug, a ‘jaw dropping’ protective HR in time to recovery of 0.2 (95% CI 0.1 to 0.35).

The tension is released and celebrations can begin… or lasix 100mg price can they?. The message in Taco Jan Pils’ and colleagues’ systematic review of trials reporting is that, even now, in the era of EQUATOR, CONSORT, siblings and half siblings safety data is often overlooked. Though reporting has improved over the decade since their previous review, it’s baffling that it isn’t 100%.

Part of lasix 100mg price the story is missing. Taking a tangential trajectory, it would be reasonable to argue that the sort of safety reporting leaves a few more loopholes. I want to know whether children can swallow the preparation.

Whether it tastes good lasix 100mg price (or at least isn’t emetogenic). And that the cost is not crippling for the health service or patients and parents by which it will ultimately be financed. This too lasix 100mg price (the economic burden) is also to my mind a side effect.

Where resources are finite, something else will have to give. Maybe that mouthwatering ‘effect size’ didn’t tell us everything we need to know. See page 1010Fixing a hole where the rain gets inThe reality is that much of what we do, despite the lasix 100mg price best public health preventative measures is reactive.

The asthmatic child’s parents of ‘who only ever smoke outside’ are advised to stop or get help/gum/patches.I’m digressing but only slightly as, what I’m getting at are the upstream (preventative) vs downstream (symptomatic) approaches. Until recently, all treatment in cystic fibrosis was, by necessity, reactive/downstream. The advent of the CF transmembrane modulator family, correctors and potentiators has changed all this lasix 100mg price.

Iolo Doull’s compelling review from the discovery of the molecule to the consistent improvements in all objective measures of lung and overall health by its augmentation testifies to this. This is exciting for other lasix 100mg price reasons too. In the same way that anti-retroviral treatment in HIV became bolder and gathered pace, there is impetus for novel orphan drug development with implications beyond CF alone.

See page 941(Pierre-)Robin sequence (RS) is characterised by mandibular retrognathia, glossoptosis and upper airway obstruction (UAO). To alleviate lasix 100mg price the latter, placing such infants prone was already suggested as a first-line treatment by Robin himself, the eponym of this condition. Indeed, it appears intuitively plausible that gravity will help shifting the mandible forward during sleep.

Against this background, it was not surprising that the prone position was implemented by about two-thirds of respondents to a recent survey focusing on interventions used in infants with RS.1In neonatology, however, we have learnt the hard way that what seems plausible is not always effective and, particularly, safe. Thus, we need lasix 100mg price to scrutinise the evidence for recommending prone positioning to resolve UAO in infants with RS. Objective data on the effectiveness of this intervention, however, are sparse.

A retrospective analysis of sleep study data in 18 infants with RS (mean age, 1.5 months) found a higher sleep efficiency in the prone position, but no significant reduction in the severity of obstructive sleep apnoea (OSA).2 A longitudinal prospective study in 14 infants with RS (mean age, 1.8 months) reported a median Obstructive Apnoea–Hypopnoea ….

60mg lasix

AdvertisementContinue reading http://buildcraft.co.in/products/single-seater-sofa/ the 60mg lasix main storySupported byContinue reading the main storyCannabis for Better Sex?. Here’s What the Science Says.The research is thin, but anecdotal experience suggests that the right dose and delivery method can make a positive difference for some people.Send any friend a storyAs a subscriber, you have 10 60mg lasix gift articles to give each month. Anyone can read what you share.391Credit...Shuhua XiongApril 1, 2022A few weeks ago, the Ask Well column highlighted treatments for low libido in women. Afterward, several readers wanted to know if cannabis could be added to the list 60mg lasix of potential remedies.It’s a question that is especially relevant now that the U.S. House of Representatives has passed a bill decriminalizing marijuana at the federal level.Marijuana, the most commonly used drug that is federally illegal, is currently allowed for medical use in 37 states, and in 18 states for adult recreational use.

According to a 2020 survey, nearly 18 percent of Americans age 12 or older had used it within the past year, and more than two-thirds of Americans support legalizing it, according to various polls.To learn more about cannabis and sex we turned to several experts, including a gynecologist who has surveyed women about 60mg lasix their marijuana use.The bottom line. It’s hard 60mg lasix to say with certainty that cannabis will increase desire or improve your sex life, but anecdotal evidence suggests that the right dose of cannabis can make a woman’s orgasms more satisfying and increase sex drive. This is in part because cannabis can enhance the senses and also alleviate some of the symptoms that inhibit desire, like anxiety, sleeplessness or pain. It can have positive effects for men, as well, but also several negative ones, and women should be aware of 60mg lasix its potential downsides, too.What does the research say?. Both men and women have long reported that cannabis alters their sexual experience.

In an essay published in 1971, the astronomer Carl Sagan, a longtime marijuana user, wrote that cannabis “enhances the enjoyment of sex” and “gives an exquisite sensitivity.”There is very little research on cannabis and libido, however, in part because cannabis research has been notoriously difficult to fund and it remains a federally 60mg lasix illegal drug in the United States. Most of the research that does exist relies on data from questionnaires, which are heavily skewed toward people who already use cannabis and are not representative of the general population, making it difficult to draw firm conclusions. In addition, the surveys do not provide reliable and precise information about dosage, delivery method or timing.But based on the limited evidence, the drug does seem to enhance the sexual experience among many women who 60mg lasix already use it.“I’ve had several patients come to me and say, ‘I have low libido. Can you help 60mg lasix me?. And, oh, by the way, if I use marijuana, I can orgasm, no problem,’” said Dr.

Becky K 60mg lasix. Lynn, a sexual medicine and menopause expert and the founder of Evora Women’s Health in St. Louis. €œThey also tell me that low libido improves with marijuana.”Dr. Lynn, who also teaches at the Saint Louis University School of Medicine, is the lead author of a study published in 2019 that surveyed 373 women about cannabis at an obstetrics and gynecology clinic in Missouri.

Of those, 34 percent reported having used marijuana before sexual activity and most of them said it resulted in an increased sex drive, improved orgasm and decreased pain.Studies have also found that some women use cannabis to help manage menopause symptoms like hot flashes, night sweats, insomnia and vaginal changes, such as dryness, all of which may contribute to lower libido when untreated.In addition, an online survey of more than 200 women and men who use cannabis found that nearly 60 percent said cannabis increased their desire for sex. Almost 74 percent reported increased sexual satisfaction. But the study, which was conducted by researchers in Canada and published in The Journal of Sexual Medicine, also said that 16 percent reported sex was better in some ways and worse in others, and a little under 5 percent said it was worse.Research on cannabis use and sexual function among men is likewise sparse and can be contradictory. According to the International Society for Sexual Medicine, some men report that their sexual performance improves when they use marijuana, while others may experience problems such as less motivation for sex, erectile dysfunction, trouble reaching orgasm or premature ejaculation. Cannabis use has also been associated with reductions in sperm count, concentration, motility and viability.‘Start low and go slow’All drugs have risks and potential side effects, cannabis included.If your doctor has cleared you to try cannabis in a state where it is legal, Dr.

Peter Grinspoon, a primary-care doctor at Massachusetts General Hospital Chelsea HealthCare Center and a medical-cannabis consultant, advised taking a “teeny bit” in a tincture if you’re new to it — in some cases as little as 1 milligram of THC, the main psychoactive ingredient in weed — before slowly working your way up.“At low doses, cannabis helps libido, but at high doses, it often isn’t as effective,” he said, adding that the wrong amount will lead some people to become paranoid and anxious. The drug could also inhibit orgasm, creating the opposite effect of what was intended.Dr. Lynn agreed. €œStart low and go slow,” she said.How much is too much marijuana?. That will vary from person to person.And because cannabis is known to impair judgment, coordination and reaction time, those who use psychoactive drugs before or during sex “must take into consideration whether people using the product and their partners can have safe and consensual sex,” said Dr.

Stacy Tessler Lindau, a gynecologist at the University of Chicago Medicine and the creator of WomanLab, a website about sexual health.Given that cannabis can compromise judgment about contraception or the ability to consent, she added, women can either look to avoid products with psychoactive components or, if they wish to use them, increase safety by having sex with a trusted partner.“Sex with a stranger ideally would not involve any intoxication of anyone involved,” she said.Dr. Jordan Tishler, a former emergency medicine doctor and president of the Association of Cannabinoid Specialists, recommended trying cannabis alone for the first few times and masturbating, in order “to understand what it does to the body and sensations.”What is the best cannabis delivery method?. Smoking marijuana or using oil vape pens should be avoided, because they can harm the lungs, the experts said.Dr. Lynn typically recommends tinctures, which are concentrated cannabis extracts that are taken by mouth. It is easy to measure the number of milligrams you want to use, she said.Dr.

Tishler usually advises his clients to start with 5 mg of THC. Taking one puff on a cannabis flower vaporizer before having a sexual experience can work faster and more predictably than edibles or lubricants infused with THC, he said.“I teach patients to take a puff in a particular manner,” Dr. Tishler added. €œa very deep, slow inhalation that allows us to estimate how much dose they are getting.”Remember that libido is complicatedThere are multiple factors that can affect someone’s sex drive and sexual function, some of which could be addressed by seeing a physician or a mental health provider.If a woman had pain with intercourse, for example, she would need to be referred to a gynecologist for a full evaluation, Dr. Grinspoon said.

Cannabis could potentially help, but there would be more to investigate and consider in anyone who is experiencing uncomfortable physical symptoms.“You can be treating the symptom while looking at the underlying cause,” he said. €œIt’s not mutually exclusive.”AdvertisementContinue reading the main storyCredit...Melissa Schriek for The New York TimesSkip to contentSkip to site indexThe Next Big Addiction TreatmentSeveral psychedelic drugs are touted as effective treatments for drug and alcohol abuse. But psilocybin combined with therapy is emerging as the most effective.Credit...Melissa Schriek for The New York TimesSupported byContinue reading the main storySend any friend a storyAs a subscriber, you have 10 gift articles to give each month. Anyone can read what you share.146March 31, 2022In recent years there has been a spate of research suggesting psychedelic drugs can help people manage mental health conditions like depression, anxiety, chronic pain or even eating disorders. But a growing body of data points to one as the leading contender to treat the intractable disease of substance abuse.

Psilocybin, the active ingredient in psychedelic mushrooms, has shown promise in limited early studies, not only in alcohol and harder drugs, but also nicotine — all of which resist long term treatment.“The old rule of thumb is that one-third of people get better, one-third stay the same, and one-third continue to get worse,” said Dr. Michael Bogenschutz, a psychiatrist at New York University’s Grossman School of Medicine studying psilocybin-assisted therapy as a treatment for alcohol abuse. €œWhat’s fascinating to me about this whole process is how many different kinds of experiences people can have, which ultimately help them make these profound changes in their behavior.”Take Aimée Jamison, who several years ago wanted to kick her cigarette habit before her 50th birthday. Statistically speaking, Ms. Jamison’s chance of success wasn’t great.

According to the Centers for Disease Control and Prevention, 55 percent of adult smokers tried to quit in 2018, but only 8 percent were successful.Ms. Jamison, an investor who lives part-time in Boston, had heard about psychedelic therapies, but the drug is largely illegal for personal use. So, in the fall of 2018, she flew to Baltimore to participate in a clinical trial at the Johns Hopkins Center for Psychedelic &. Consciousness Research. When she had to abstain from nicotine for a day before a brain scan, she could barely sleep and called it “the most hellish 24 hours I’ve experienced.”After three talk therapy sessions at the Hopkins clinic, she was given a single pill containing 30 milligrams of psilocybin, a relatively high dose.

After swallowing the pill, she put on an eye-mask, laid on a couch and went on a psychedelic trip with two therapists nearby for the next five hours.When her trip ended, she sat up and looked at the therapists. €œNow, I understand why I smoked,” she said, “and I don’t need to do that anymore.”Over the next couple months Ms. Jamison attended several more therapy sessions, but took no additional psilocybin. She hasn’t touched a cigarette in the years since. An early version of that study (in which participants had two or three psilocybin sessions), published in 2014, reported an 80 percent success rate in 15 smokers, compared with 35 percent typically observed in patients taking the leading conventional antismoking drug Chantix.Buoyed by such positive outcomes, the Hopkins study has expanded to include more participants, and, last year, the team received a $4 million grant from the National Institutes of Health.It’s still uncertain how effective using psilocybin to treat addiction is in the long-term and whether some individuals are more likely to benefit than others.

Some study participants have had troubling experiences during their trips, and experts say that people should not be taking the drug outside of legitimate research studies or without medical supervision.The five-hour duration of the experience will also make it costly in a health care setting, which could limit its use in lower-income communities disproportionately affected by drug and alcohol abuse. Still, many experts hungry for new addiction therapies say that psilocybin represents a new and potentially exciting treatment for people suffering from a disease that is difficult to address.Treating more than a chemical dependencyOne of the reasons addictions are so hard to treat is that most are more than chemical dependency. Long after the short-term withdrawals have waned, people suffering from addiction often face living without the stress release valve that their habit gave them. Those wishing to quit may persevere for a few weeks or months, but when stressed or upset, their brains often divert them back to the familiar territory of their addiction.Some experts say psilocybin addresses that psychological need. Along with LSD and mescaline, it is known as a “classic psychedelic,” which activates switches in the brain’s visual cortex, the serotonin 5-HT2a receptors, producing hallucinations.

Back in the psychedelic heyday of the 1950s and 1960s, such drugs were evaluated for treating depression and addiction with mixed results.But that work was put on ice in the 1970s with the passage of the Controlled Substances Act, which placed LSD and psilocybin in the most restrictive legal category, known as Schedule 1.Thirty years later, in 2000, Roland Griffiths, a psychopharmacologist at Johns Hopkins, received the green light from the Food and Drug Administration to study the psychological effects of psilocybin on 30 volunteers. In a survey given to participants two months after their session, more than half ranked it as among the most meaningful experiences of their lives.Psychedelic research has blossomed since then. A British study published earlier this year found that people with severe alcohol abuse disorder who received ketamine-assisted therapy abstained from drinking 10 percent more over six months than those who received just a placebo along with therapy or education.Some studies on ketamine and addiction, however, suggest that its antidepressant effect wears off over time, and participants may need repeated infusions. This is a potential problem because the drug itself has the potential to become a drug of abuse and overdoses can, in rare cases, be fatal.Researchers who are enthusiastic about psilocybin say its longer, more intense psychedelic experience make it a more long-lasting therapeutic. It generally requires just a single session or sometimes several sessions to be effective, provided it’s integrated with psychotherapy or some other form of counseling.“People have greater mental flexibility following psilocybin,” said Matthew Johnson, a psychologist at Johns Hopkins who leads the smoking trial.

€œThat increase in openness might be a permanent change that can help in overcoming addiction.”An uncertain futureAlthough psilocybin remains illegal under federal drug laws, some cities, including Denver, and Santa Cruz, Calif., have decriminalized it. Oregon, in November 2020, voted to become the first state to legalize it for medical use.Psilocybin is considered safer than ketamine and is not habit-forming, but it does have its downsides. The greatest risks may come from a person who uses the drug alone and wanders into traffic or other dangerous situations while high. Even in the supervised setting of a research laboratory, users often experience side effects, such as vomiting or loss of coordination, and the trip itself can produce anxiety, pain or even a psychotic break.“One of the big challenges of these treatments is that the effects are somewhat unpredictable,” Dr. Bogenschutz said.The California Institute of Integral Studies is one of the best known organizations offering a certificate program to train future therapists working with psychedelics, but since psilocybin-assisted therapy remains illegal, an underground treatment market has popped up around the country.Jon Kostakopoulos, a former alcoholic who founded the Apollo Pact, a nonprofit that advocates for increased federal funding of psilocybin research, said that the psychedelic landscape can be tough for people to navigate.

He said he has spoken to several people who became suicidal after their psychedelic guides told them to quit taking their conventional antidepressant medications in preparation for their psilocybin trip. Mr. Kostakopoulos tries to direct people to legitimate clinical trials, like the pilot study he took part in at N.Y.U. And which he believes helped him to give up alcohol.“I think you need to do this with properly trained professionals,” he said. €œThere are some shady actors.”Some also some worry that psilocybin is not being evaluated in the poorer communities where addiction has its greatest toll.

€œWe need to develop treatments to help everyone,” said Peter Hendricks, a psychologist who studies psilocybin and addiction at the University of Alabama in Birmingham.He is nearing the conclusion of a clinical trial that has stretched on for more than five years, which aims to evaluate the potential of psilocybin as a treatment for cocaine abuse. He focused on recruiting users from low income communities around Birmingham, including among the homeless, where addiction is rampant.On its own, psychotherapy is not generally an effective treatment for cocaine use disorder. In Dr. Hendricks’s trial, however, a preliminary analysis of the first 10 participants showed that those who received psilocybin along with therapy used cocaine on fewer days over the next six months than those who received a placebo alongside therapy. They also reported that it was significantly easier to abstain from cocaine and reported higher life satisfaction.Dr.

Hendricks, however, warns that people shouldn’t get their hopes up too high. €œThe existing treatments are very ineffective,” he said. €œI’m hoping to go from pretty darn ineffective to not bad or decent.”Brendan Borrell is a journalist in Los Angeles and the author of “The First Shots. The Epic Rivalries and Heroic Science Behind the Race to the hypertension treatment.”AdvertisementContinue reading the main story.

AdvertisementContinue reading the main lasix 100mg price storySupported byContinue reading the main storyCannabis for Better Sex?. Here’s What the Science Says.The research lasix 100mg price is thin, but anecdotal experience suggests that the right dose and delivery method can make a positive difference for some people.Send any friend a storyAs a subscriber, you have 10 gift articles to give each month. Anyone can read what you share.391Credit...Shuhua XiongApril 1, 2022A few weeks ago, the Ask Well column highlighted treatments for low libido in women.

Afterward, several readers lasix 100mg price wanted to know if cannabis could be added to the list of potential remedies.It’s a question that is especially relevant now that the U.S. House of Representatives has passed a bill decriminalizing marijuana at the federal level.Marijuana, the most commonly used drug that is federally illegal, is currently allowed for medical use in 37 states, and in 18 states for adult recreational use. According to a 2020 survey, lasix 100mg price nearly 18 percent of Americans age 12 or older had used it within the past year, and more than two-thirds of Americans support legalizing it, according to various polls.To learn more about cannabis and sex we turned to several experts, including a gynecologist who has surveyed women about their marijuana use.The bottom line.

It’s hard to say with certainty that cannabis lasix 100mg price will increase desire or improve your sex life, but anecdotal evidence suggests that the right dose of cannabis can make a woman’s orgasms more satisfying and increase sex drive. This is in part because cannabis can enhance the senses and also alleviate some of the symptoms that inhibit desire, like anxiety, sleeplessness or pain. It can have positive effects for men, as well, but also lasix 100mg price several negative ones, and women should be aware of its potential downsides, too.What does the research say?.

Both men and women have long reported that cannabis alters their sexual experience. In an essay published in 1971, the astronomer Carl Sagan, a longtime marijuana user, wrote that cannabis “enhances the enjoyment of sex” and “gives an exquisite sensitivity.”There is very little research on cannabis and libido, however, in part lasix 100mg price because cannabis research has been notoriously difficult to fund and it remains a federally illegal drug in the United States. Most of the research that does exist relies on data from questionnaires, which are heavily skewed toward people who already use cannabis and are not representative of the general population, making it difficult to draw firm conclusions.

In addition, the surveys do not provide reliable and precise information about dosage, delivery method or timing.But based on the limited evidence, the drug does seem to enhance the sexual experience among many lasix 100mg price women who already use it.“I’ve had several patients come to me and say, ‘I have low libido. Can you lasix 100mg price help me?. And, oh, by the way, if I use marijuana, I can orgasm, no problem,’” said Dr.

Becky K lasix 100mg price. Lynn, a sexual medicine and menopause expert and the founder of Evora Women’s Health in St. Louis.

€œThey also tell me that low libido improves with marijuana.”Dr. Lynn, who also teaches at the Saint Louis University School of Medicine, is the lead author of a study published in 2019 that surveyed 373 women about cannabis at an obstetrics and gynecology clinic in Missouri. Of those, 34 percent reported having used marijuana before sexual activity and most of them said it resulted in an increased sex drive, improved orgasm and decreased pain.Studies have also found that some women use cannabis to help manage menopause symptoms like hot flashes, night sweats, insomnia and vaginal changes, such as dryness, all of which may contribute to lower libido when untreated.In addition, an online survey of more than 200 women and men who use cannabis found that nearly 60 percent said cannabis increased their desire for sex.

Almost 74 percent reported increased sexual satisfaction. But the study, which was conducted by researchers in Canada and published in The Journal of Sexual Medicine, also said that 16 percent reported sex was better in some ways and worse in others, and a little under 5 percent said it was worse.Research on cannabis use and sexual function among men is likewise sparse and can be contradictory. According to the International Society for Sexual Medicine, some men report that their sexual performance improves when they use marijuana, while others may experience problems such as less motivation for sex, erectile dysfunction, trouble reaching orgasm or premature ejaculation.

Cannabis use has also been associated with reductions in sperm count, concentration, motility and viability.‘Start low and go slow’All drugs have risks and potential side effects, cannabis included.If your doctor has cleared you to try cannabis in a state where it is legal, Dr. Peter Grinspoon, a primary-care doctor at Massachusetts General Hospital Chelsea HealthCare Center and a medical-cannabis consultant, advised taking a “teeny bit” in a tincture if you’re new to it — in some cases as little as 1 milligram of THC, the main psychoactive ingredient in weed — before slowly working your way up.“At low doses, cannabis helps libido, but at high doses, it often isn’t as effective,” he said, adding that the wrong amount will lead some people to become paranoid and anxious. The drug could also inhibit orgasm, creating the opposite effect of what was intended.Dr.

Lynn agreed. €œStart low and go slow,” she said.How much is too much marijuana?. That will vary from person to person.And because cannabis is known to impair judgment, coordination and reaction time, those who use psychoactive drugs before or during sex “must take into consideration whether people using the product and their partners can have safe and consensual sex,” said Dr.

Stacy Tessler Lindau, a gynecologist at the University of Chicago Medicine and the creator of WomanLab, a website about sexual health.Given that cannabis can compromise judgment about contraception or the ability to consent, she added, women can either look to avoid products with psychoactive components or, if they wish to use them, increase safety by having sex with a trusted partner.“Sex with a stranger ideally would not involve any intoxication of anyone involved,” she said.Dr. Jordan Tishler, a former emergency medicine doctor and president of the Association of Cannabinoid Specialists, recommended trying cannabis alone for the first few times and masturbating, in order “to understand what it does to the body and sensations.”What is the best cannabis delivery method?. Smoking marijuana or using oil vape pens should be avoided, because they can harm the lungs, the experts said.Dr.

Lynn typically recommends tinctures, which are concentrated cannabis extracts that are taken by mouth. It is easy to measure the number of milligrams you want to use, she said.Dr. Tishler usually advises his clients to start with 5 mg of THC.

Taking one puff on a cannabis flower vaporizer before having a sexual experience can work faster and more predictably than edibles or lubricants infused with THC, he said.“I teach patients to take a puff in a particular manner,” Dr. Tishler added. €œa very deep, slow inhalation that allows us to estimate how much dose they are getting.”Remember that libido is complicatedThere are multiple factors that can affect someone’s sex drive and sexual function, some of which could be addressed by seeing a physician or a mental health provider.If a woman had pain with intercourse, for example, she would need to be referred to a gynecologist for a full evaluation, Dr.

Grinspoon said. Cannabis could potentially help, but there would be more to investigate and consider in anyone who is experiencing uncomfortable physical symptoms.“You can be treating the symptom while looking at the underlying cause,” he said. €œIt’s not mutually exclusive.”AdvertisementContinue reading the main storyCredit...Melissa Schriek for The New York TimesSkip to contentSkip to site indexThe Next Big Addiction TreatmentSeveral psychedelic drugs are touted as effective treatments for drug and alcohol abuse.

But psilocybin combined with therapy is emerging as the most effective.Credit...Melissa Schriek for The New York TimesSupported byContinue reading the main storySend any friend a storyAs a subscriber, you have 10 gift articles to give each month. Anyone can read what you share.146March 31, 2022In recent years there has been a spate of research suggesting psychedelic drugs can help people manage mental health conditions like depression, anxiety, chronic pain or even eating disorders. But a growing body of data points to one as the leading contender to treat the intractable disease of substance abuse.

Psilocybin, the active ingredient in psychedelic mushrooms, has shown promise in limited early studies, not only in alcohol and harder drugs, but also nicotine — all of which resist long term treatment.“The old rule of thumb is that one-third of people get better, one-third stay the same, and one-third continue to get worse,” said Dr. Michael Bogenschutz, a psychiatrist at New York University’s Grossman School of Medicine studying psilocybin-assisted therapy as a treatment for alcohol abuse. €œWhat’s fascinating to me about this whole process is how many different kinds of experiences people can have, which ultimately help them make these profound changes in their behavior.”Take Aimée Jamison, who several years ago wanted to kick her cigarette habit before her 50th birthday.

Statistically speaking, Ms. Jamison’s chance of success wasn’t great. According to the Centers for Disease Control and Prevention, 55 percent of adult smokers tried to quit in 2018, but only 8 percent were successful.Ms.

Jamison, an investor who lives part-time in Boston, had heard about psychedelic therapies, but the drug is largely illegal for personal use. So, in the fall of 2018, she flew to Baltimore to participate in a clinical trial at the Johns Hopkins Center for Psychedelic &. Consciousness Research.

When she had to abstain from nicotine for a day before a brain scan, she could barely sleep and called it “the most hellish 24 hours I’ve experienced.”After three talk therapy sessions at the Hopkins clinic, she was given a single pill containing 30 milligrams of psilocybin, a relatively high dose. After swallowing the pill, she put on an eye-mask, laid on a couch and went on a psychedelic trip with two therapists nearby for the next five hours.When her trip ended, she sat up and looked at the therapists. €œNow, I understand why I smoked,” she said, “and I don’t need to do that anymore.”Over the next couple months Ms.

Jamison attended several more therapy sessions, but took no additional psilocybin. She hasn’t touched a cigarette in the years since. An early version of that study (in which participants had two or three psilocybin sessions), published in 2014, reported an 80 percent success rate in 15 smokers, compared with 35 percent typically observed in patients taking the leading conventional antismoking drug Chantix.Buoyed by such positive outcomes, the Hopkins study has expanded to include more participants, and, last year, the team received a $4 million grant from the National Institutes of Health.It’s still uncertain how effective using psilocybin to treat addiction is in the long-term and whether some individuals are more likely to benefit than others.

Some study participants have had troubling experiences during their trips, and experts say that people should not be taking the drug outside of legitimate research studies or without medical supervision.The five-hour duration of the experience will also make it costly in a health care setting, which could limit its use in lower-income communities disproportionately affected by drug and alcohol abuse. Still, many experts hungry for new addiction therapies say that psilocybin represents a new and potentially exciting treatment for people suffering from a disease that is difficult to address.Treating more than a chemical dependencyOne of the reasons addictions are so hard to treat is that most are more than chemical dependency. Long after the short-term withdrawals have waned, people suffering from addiction often face living without the stress release valve that their habit gave them.

Those wishing to quit may persevere for a few weeks or months, but when stressed or upset, their brains often divert them back to the familiar territory of their addiction.Some experts say psilocybin addresses that psychological need. Along with LSD and mescaline, it is known as a “classic psychedelic,” which activates switches in the brain’s visual cortex, the serotonin 5-HT2a receptors, producing hallucinations. Back in the psychedelic heyday of the 1950s and 1960s, such drugs were evaluated for treating depression and addiction with mixed results.But that work was put on ice in the 1970s with the passage of the Controlled Substances Act, which placed LSD and psilocybin in the most restrictive legal category, known as Schedule 1.Thirty years later, in 2000, Roland Griffiths, a psychopharmacologist at Johns Hopkins, received the green light from the Food and Drug Administration to study the psychological effects of psilocybin on 30 volunteers.

In a survey given to participants two months after their session, more than half ranked it as among the most meaningful experiences of their lives.Psychedelic research has blossomed since then. A British study published earlier this year found that people with severe alcohol abuse disorder who received ketamine-assisted therapy abstained from drinking 10 percent more over six months than those who received just a placebo along with therapy or education.Some studies on ketamine and addiction, however, suggest that its antidepressant effect wears off over time, and participants may need repeated infusions. This is a potential problem because the drug itself has the potential to become a drug of abuse and overdoses can, in rare cases, be fatal.Researchers who are enthusiastic about psilocybin say its longer, more intense psychedelic experience make it a more long-lasting therapeutic.

It generally requires just a single session or sometimes several sessions to be effective, provided it’s integrated with psychotherapy or some other form of counseling.“People have greater mental flexibility following psilocybin,” said Matthew Johnson, a psychologist at Johns Hopkins who leads the smoking trial. €œThat increase in openness might be a permanent change that can help in overcoming addiction.”An uncertain futureAlthough psilocybin remains illegal under federal drug laws, some cities, including Denver, and Santa Cruz, Calif., have decriminalized it. Oregon, in November 2020, voted to become the first state to legalize it for medical use.Psilocybin is considered safer than ketamine and is not habit-forming, but it does have its downsides.

The greatest risks may come from a person who uses the drug alone and wanders into traffic or other dangerous situations while high. Even in the supervised setting of a research laboratory, users often experience side effects, such as vomiting or loss of coordination, and the trip itself can produce anxiety, pain or even a psychotic break.“One of the big challenges of these treatments is that the effects are somewhat unpredictable,” Dr. Bogenschutz said.The California Institute of Integral Studies is one of the best known organizations offering a certificate program to train future therapists working with psychedelics, but since psilocybin-assisted therapy remains illegal, an underground treatment market has popped up around the country.Jon Kostakopoulos, a former alcoholic who founded the Apollo Pact, a nonprofit that advocates for increased federal funding of psilocybin research, said that the psychedelic landscape can be tough for people to navigate.

He said he has spoken to several people who became suicidal after their psychedelic guides told them to quit taking their conventional antidepressant medications in preparation for their psilocybin trip. Mr. Kostakopoulos tries to direct people to legitimate clinical trials, like the pilot study he took part in at N.Y.U.

And which he believes helped him to give up alcohol.“I think you need to do this with properly trained professionals,” he said. €œThere are some shady actors.”Some also some worry that psilocybin is not being evaluated in the poorer communities where addiction has its greatest toll. €œWe need to develop treatments to help everyone,” said Peter Hendricks, a psychologist who studies psilocybin and addiction at the University of Alabama in Birmingham.He is nearing the conclusion of a clinical trial that has stretched on for more than five years, which aims to evaluate the potential of psilocybin as a treatment for cocaine abuse.

He focused on recruiting users from low income communities around Birmingham, including among the homeless, where addiction is rampant.On its own, psychotherapy is not generally an effective treatment for cocaine use disorder. In Dr. Hendricks’s trial, however, a preliminary analysis of the first 10 participants showed that those who received psilocybin along with therapy used cocaine on fewer days over the next six months than those who received a placebo alongside therapy.

They also reported that it was significantly easier to abstain from cocaine and reported higher life satisfaction.Dr. Hendricks, however, warns that people shouldn’t get their hopes up too high. €œThe existing treatments are very ineffective,” he said.

€œI’m hoping to go from pretty darn ineffective to not bad or decent.”Brendan Borrell is a journalist in Los Angeles and the author of “The First Shots. The Epic Rivalries and Heroic Science Behind the Race to the hypertension treatment.”AdvertisementContinue reading the main story.