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PubhD: Cell Origins, Biofilms & Vibrations
January 20 @ 7:00 pm - 8:30 pmFree
Speakers and topics:
Amy Muir – Cell Origins
In my project I hope to identify the cell of origin where a specific high risk cancer causing mutation arises in childhood leukaemia. This will help improve the understanding of disease development and progression. Identifying markers of this leukaemia subtype will be a clinically useful tool for identifying the disease at diagnosis and allow for the better targeting of therapeutics to rapidly treat this specific leukaemia subtype.
Liam Rooney – Biofilms
We study communities of bacteria called biofilms which, due to their structural composition, are resistant to mechanical and chemical clearing. Using new groundbreaking microscopy methods we are able to image multi-multimeter sized biofilms while simultaneously observing individual live bacteria. In doing so we have discovered networks of protein-based channels which permeate biofilms and can be used to facilitate nutrient uptake into these dense microbial communities. Furthermore we have exploited this beneficial function to “trick” the biofilm in taking in antibiotics through the channels to kill the biofilm from the inside out (almost like blowing up a bacterial Death Star). Our work offers new insights to microbial community dynamics, and a mechanism by which biofilm clearing can be promoted to lower their burden on public health and in industry.
Alex Elliott – Vibrations
My work involves mathematical modelling for the vibrations of cutting-edge engineering structures, for which the traditional methods no longer work. I started by taking a fundamental look at why these structures need to be treated differently and why it is often necessary to approximate the behaviour, rather than compute it directly. The majority of my work looks at how accurate these approximations are and how we can improve this accuracy.
The format is nice and simple:
1: Three researchers will each have 10 minutes to talk about their subject area to an interested audience in a pub
2: There will be up to 20 minutes of (friendly!) Q&A per speaker.
3: Each speaker gets at least one pint (or other drink of their choice).
A whiteboard/flip chart and coloured pens will be provided.
Kickoff at 7pm sharp. Drop-in event … no tickets required
This is event is free to attend, although we will be asking for donations at the end of the talk. Participants are under no obligation whatsoever to donate, however please rest assured that the money we collect doesn’t end up in anyone’s pocket – it is used to fund our overhead costs, and travel/accommodation for our speakers who come from further afield.
Accessibility: The talk is on the top floor of the store, however there is however a lift available for customers to use.